Validated biomarkers have rapidly become essential tools in many aspects of discovery research and diagnostics, with the emergence of Personalized Medicine driving this need all the more. Proteome Sciences has been at the forefront of Proteomics research and discovery since the early 1990s, and has a long and successful track record in discovering new and valuable biomarkers to further drug discovery and clinical applications. Our PS Biomarker ServicesTM is fast becoming the preferred provider of services for biomarker and target-related proteomics services to the pharmaceutical sector.
We offer a variety of pre-configured assays, with an emphasis in the areas of Central Nervous System disorders, Oncology and Stroke (see disease specific assay pages). We use the very latest in sample preparation & separation techniques, isotopic and isobaric labeling and label-free sample analysis platforms and data analysis tools at our ISO 9001:2008 accredited facility. Our PS Biomarker DiscoveryTM Consulting Service provides access to extensive custom assay development options for a wide range of disease model and human sample types. Consult with our expert scientific team of protein chemists, mass spectrometrists, bioinformaticians and medical researchers for your specific biomarker service needs.
No other service provider has the breadth of leading technology platforms nor the large team of highly trained and experienced scientists for protein biomarkers
At the core of Proteome Sciences technologies and expertise, is a first-in-class mass spectrometry capability for the detection and accurate quantitation of biomarkers. Many assays utilize Proteome Sciences’ proprietary Tandem Mass Tag® (TMT®) labeling technology to ensure the most accurate and consistent results expected by today’s researchers.
Mass spectrometry permits the rapid identification of novel biomarkers from a far greater spectrum of the proteome than can be achieved using an immunoassay approach alone
of custom biomarker strategies, we are unique in providing a full service offering to complement all phases in the development of new drugs and new diagnostic products.
Our extensive service offering includes:
- Specialist consultancy during project design and initiation
- Pre-determined sample collection, processing and shipment protocols
- Pre-analytical sample QC
- Protein extraction with TMT-labeling
- Choice of proteomic and peptidomic workflows
- Reproducible protein separation
- First-in-class mass spectrometry
- Dedicated bioinformatics for biomarker discovery/validation
- Comprehensive reporting
- Goal-oriented project management process
- SysQuant Assay
- MS3 TMT Workflow
PS Biomarker Services-Typical Work Flow:
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