Sample Quality Control
Rigorous Quality Control Protocols Ensure Accurate & Reliable Results
Biomarker discovery and validation demands the highest possible sample quality, yet a lack of appropriate assessment of sample quality prior to analysis is a common failing of many biomarker projects. Proteome Sciences helps you avoid this major pitfall by employing rigorous and strict protocols to ensure safe and secure sample handling, preparation and pre-analytical assessment of integrity. Quality control of samples and procedures is performed to the highest of standards providing you the confidence of getting the absolute best quality of results for your research. Equipped to handle all types of samples from plasma, serum, CSF, tissues, cells, FFPE (Formalin-Fixed Paraffin-Embedded tissue), urine, proteins and peptides, we have a dedicated staff and sample preparation laboratory at our ISO 9001:2008 accredited testing facility.
Exemplary quality control procedures yields results you can trust every time
The peptide content profile of a sample indicates the overall quality and integrity of that sample. The presence of contaminants or characteristic break-down products (proteolytic fragments) provide a direct measure of sample quality. Thus, evidence of incorrect sample collection, preparation, storage or shipping can be identified before results are compromised.
Routine sample QC for biomarker studies is performed using a simple mass spectrometry workflow before and during analytical runs. All samples are compared to reference samples and assigned a score correlating with sample integrity. Outlier analysis and cluster analysis is performed on QC samples, with suspect sample profiles being flagged and subjected to further statistical analysis to identify particular sample artifacts and likely causes of sample degradation or contamination.
Learn more about our QC CSF Assay
designed to reliably assess the quality of patient Cerebrospinal Fluid samples.
Client-only sample preparation laboratory under ISO 9001:2008 QMS
You can be secure in the knowledge that all samples are received into a dedicated client-only sample preparation laboratory, logged into our bespoke laboratory information management system (LIMS) and assigned a unique study number allowing continuous sample tracking. We can handle up to ≥1,000 samples per month.
Our clients benefit from our many years of experience in handling and analyzing samples from diverse biological origin. We offer expert consulting with our scientific staff to determine the optimal customized work plan for sample collection, processing, shipping and QC requirements for your specific biomarker studies.