Goal - Expand the utility of CSF in the management of dementia.
Outcome – A targeted mass spectrometry assay for 16 CSF proteins selected from previous discovery experiments and literature review demonstrated excellent diagnostic performance when applied to a cohort of 94 samples (59 AD and 35 non-AD controls).
Collaborators The Sahlgrenska Academy at the University of Gothenburg
Product - Biomarker Discovery & TMT®SRM
Goal – Produce in-vitro assays for potential skin or lung sensitizers.
Outcome - >200 novel biomarkers identified in discovery, SensiDerm TMT®SRM 8plex assay developed to validate the top 8 markers.
Goal – Discovery and validation of biomarkers to assess the response to cMet inhibition and functional inactivation
Outcome - 170 novel biomarkers identified in discovery, BioTag TMT®SRM assay developed to validate the top 28 markers
Collaborators - ProQinase GmBH, Germany & Natural Medical Sciences Institute, University of Tubingen, Germany