Clusterin Glycosylation – A Prognostic AD Plasma Biomarker

SRM Assay Development

Goal – Characterize plasma clusterin glycosylation associated with increasing brain atrophy. 

Outcome – Eight β64N clusterin glycoforms were associated with hippocampal atrophy in AD. A targeted SRM assay is now in-development.

Collaborators Institute of Psychiatry, Kings College London and University of Oxford

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