Differentiating Fast and Slow Progressing ALS

TMTcalibrator™ Tissue-Enhanced Fluid Proteomics

Goal – Identification of blood biomarkers differentiating between fast and slow progressing forms of bulbar and limb endophenotypes of ALS.

Outcome – We have defined a list of candidate blood biomarkers predicting the subsequent rate of disease progression for stratification of ALS patients at the time of diagnosis. These may aid selection of personalized treatment options.

Collaborators - Dr. Andrea Malaspina, Queen Mary’s University, London, Professor Linda Greensmith, University College London

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