Notification of Interests in Shares
Last Updated 13 October 2025
(a) Directors and their interests
| Name of Director | Number of Ordinary Shares of 1p each |
Percent of current issued share capital |
|---|---|---|
| C.D.J. Pearce | 36,915,059 | 12.51 |
| Dr I Pike | 165,583 | 0.06 |
| Roger McDowell | 3,400,000 | 1.15 |
| Martin Diggle* | - | - |
| Richard Dennis | 625,000 | 0.21 |
(b) Significant Shareholders
| Name of Shareholder | Number of Ordinary Shares of 1p each |
Percent of Current issued share capital |
|---|---|---|
| Vulpes Life Science Fund | 67,789,772 | 22.97 |
Notes:
-The current issued share capital of the company consists of 295,182,056 Ordinary shares of 1p each. There are 36.8% of AIM securities not in public hands.
-M. Diggle is a director and partner in Vulpes Investment Management and manages the Vulpes Life Sciences Fund which is the registered holder of 22.97% of Proteome Sciences' ordinary share capital as noted above.