Publications 
Interrelationship between the Levels of C9orf72 and Amyloid-β Protein Precursor and Amyloid-β in Human Cells and Brain Samples
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Publisher:
Journal of Alzheimer's disease 62(1):269-278 DOI: 10.3233/JAD-170362
The proteome of neurofilament-containing protein aggregates in blood
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Authors:
R. Adiutori et al.
Publisher:
Biochemistry and Biophysics Reports 14, Pages 168-177
Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis
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Publisher:
Molecular Neurodegeneration 13(1) DOI: 10.1186/s13024-018-0292-2
A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology
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Combined tissue and fluid proteomics with Tandem Mass Tags to identify low abundant protein biomarkers of disease in peripheral body fluid: An Alzheimer's Disease case study
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Authors:
Russell CL, Heslegrave A, Mitra V, Zetterberg H, Pocock JM, Ward MA, Pike I
Comprehensive Quantitative Profiling of Tau and Phosphorylated Tau Peptides in Cerebrospinal Fluid by Mass Spectrometry Provides New Biomarker Candidate
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Authors:
Claire L. Russell, Vikram Mitra, Karl Hansson, Kaj Blennow, Johan Gobom, Henrik Zetterber, Mikko Hiltunen, Malcolm Ward and Ian Pike
Tandem mass tags: a novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS
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Authors:
Thompson A, Schäfer J, Kuhn K, Kienle S, Schwarz J, Schmidt G, Neumann T, Johnstone R, Mohammed AK, Hamon C.
Carbonyl-reactive tandem mass tags for the proteome-wide quantification of N-linked glycans
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Authors:
Hahne H, Neubert P, Kuhn K, Etienne C, Bomgarden R, Rogers JC, Kuster B.
Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses.
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Authors:
McAlister GC, Huttlin EL, Haas W, Ting L, Jedrychowski MP, Rogers JC, Kuhn K, Pike I, Grothe RA, Blethrow JD, Gygi SP.
Low-pH Solid-Phase Amino Labeling of Complex Peptide Digests with TMTs Improves Peptide Identification Rates for Multiplexed Global Phosphopeptide Analysis.
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Authors:
Böhm G, Prefot P, Jung S, Selzer S, Mitra V, Britton D, Kuhn K, Pike I, Thompson AH.
Quantitation of protein post-translational modifications using isobaric tandem mass tags.
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Authors:
Liang HC, Lahert E, Pike I, Ward M.
Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets.
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Authors:
Britton D, Zen Y, Quaglia A, Selzer S, Mitra V, Löβner C, Jung S, Böhm G, Schmid P, Prefot P, Hoehle C, Koncarevic S, Gee J, Nicholson R, Ward M, Castellano L, Stebbing J, Zucht HD, Sarker D, Heaton N, Pike I.
Isobaric tagging-based selection and quantitation of cerebrospinal fluid tryptic peptides with reporter calibration curves.
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Authors:
Dayon L, Turck N, Kienle S, Schulz-Knappe P, Hochstrasser DF, Scherl A, Sanchez JC.
Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis.
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Authors:
Hanger DP, Byers HL, Wray S, Leung KY, Saxton MJ, Seereeram A, Reynolds CH, Ward MA, Anderton BH.
Tyrosine phosphorylation of tau by the SRC family kinases Lck and Fyn.
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Authors:
Scales TM, Derkinderen P, Leung KY, Byers HL, Ward MA, Price C, Bird IN, Perera T, Kellie S, Williamson R, Anderton BH, Reynolds CH.
Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin.
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Authors:
Cuchillo-Ibanez I, Seereeram A, Byers HL, Leung KY, Ward MA, Anderton BH, Hanger DP.
The neuronal adaptor protein Fe65 is phosphorylated by mitogen-activated protein kinase (ERK1/2).
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Authors:
Standen CL, Perkinton MS, Byers HL, Kesavapany S, Lau KF, Ward M, McLoughlin D, Miller CC.
p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis.
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Authors:
Ackerley S, Grierson AJ, Banner S, Perkinton MS, Brownlees J, Byers HL, Ward M, Thornhill P, Hussain K, Waby JS, Anderton BH, Cooper JD, Dingwall C, Leigh PN, Shaw CE, Miller CC.
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth.
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Authors:
Tudor EL, Perkinton MS, Schmidt A, Ackerley S, Brownlees J, Jacobsen NJ, Byers HL, Ward M, Hall A, Leigh PN, Shaw CE, McLoughlin DM, Miller CC.
Reversible cysteine-targeted oxidation of proteins during renal oxidative stress.
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Authors:
Eaton P1, Jones ME, McGregor E, Dunn MJ, Leeds N, Byers HL, Leung KY, Ward MA, Pratt JR, Shattock MJ
In-depth profiling of the peripheral blood mononuclear cells proteome for clinical blood proteomics
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Authors:
Končarević S, Lößner C, Kuhn K, Prinz T, Pike I, Zucht HD.
Protein expression profiles of chemo-resistant mixed phenotype liver tumors using laser microdissection and LC-MS/MS proteomics
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Authors:
Zen Y, Britton D, Mitra V, Brand A, Jung S, Löβner C, Ward M, Pike I, Heaton N, Quaglia A
A global proteomic study identifies distinct pathological features of IgG4-related and primary sclerosing cholangitis.
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Authors:
Zen Y, Britton D, Mitra V, Pike I, Heaton N, Quaglia A.
Tubulin β-III: a novel immunohistochemical marker for intrahepatic peripheral cholangiocarcinoma.
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Authors:
Zen Y, Britton D, Mitra V, Pike I, Sarker D, Itoh T, Heaton N, Quaglia A.
Comparison of the nuclear proteomes of mammary epithelial cells at different stages of functional differentiation.
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Authors:
Desrivières S, Kuhn K, Müller J, Gläser M, Laria NC, Korder J, Sonnentag M, Neumann T, Schwarz J, Schäfer J, Hamon C, Groner B, Prinz T.
Proteomics for brain disorders-the promise for biomarkers.
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Authors:
Ward M, Güntert A, Campbell J, Pike I.
Post-translational modifications in Alzheimer's disease and the potential for new biomarkers.
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Authors:
Russell CL, Koncarevic S, Ward MA.
Comparison of a protein-level and peptide-level labeling strategy for quantitative proteomics of synaptosomes using isobaric tags.
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Authors:
Engmann O, Campbell J, Ward M, Giese KP, Thompson AJ.
Identification of proteins of Neisseria meningitidis induced under iron-limiting conditions using the isobaric tandem mass tag (TMT) labeling approach.
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Authors:
van Ulsen P, Kuhn K, Prinz T, Legner H, Schmid P, Baumann C, Tommassen J.
Detection, quantitation, purification, and identification of cardiac proteins S-thiolated during ischemia and reperfusion.
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Authors:
Eaton P, Byers HL, Leeds N, Ward MA, Shattock MJ.
beta-Actin regulates platelet nitric oxide synthase 3 activity through interaction with heat shock protein 90.
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Authors:
Ji Y1, Ferracci G, Warley A, Ward M, Leung KY, Samsuddin S, Lévêque C, Queen L, Reebye V, Pal P, Gkaliagkousi E, Seager M, Ferro A.
An integrated workflow for multiplex CSF proteomics and peptidomics-identification of candidate cerebrospinal fluid biomarkers of Alzheimer's disease.
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Authors:
Hölttä M, Minthon L, Hansson O, Holmén-Larsson J, Pike I, Ward M, Kuhn K, Rüetschi U, Zetterberg H, Blennow K, Gobom J.
Relative quantification of proteins in human cerebrospinal fluids by MS/MS using 6-plex isobaric tags.
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Authors:
Dayon L, Hainard A, Licker V, Turck N, Kuhn K, Hochstrasser DF, Burkhard PR, Sanchez JC.
Proteome-based plasma biomarkers for Alzheimer's disease.
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Authors:
Hye A, Lynham S, Thambisetty M, Causevic M, Campbell J, Byers HL, Hooper C, Rijsdijk F, Tabrizi SJ, Banner S, Shaw CE, Foy C, Poppe M, Archer N, Hamilton G, Powell J, Brown RG, Sham P, Ward M, Lovestone S.
Plasma proteins predict conversion to dementia from prodromal disease.
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Authors:
Hye A, Riddoch-Contreras J, Baird AL, Ashton NJ, Bazenet C, Leung R, Westman E, Simmons A, Dobson R, Sattlecker M, Lupton M, Lunnon K, Keohane A, Ward M, Pike I, Zucht HD, Pepin D, Zheng W, Tunnicliffe A, Richardson J, Gauthier S, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S.
AddNeuroMed-the European collaboration for the discovery of novel biomarkers for Alzheimer's disease.
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Authors:
Lovestone S1, Francis P, Kloszewska I, Mecocci P, Simmons A, Soininen H, Spenger C, Tsolaki M, Vellas B, Wahlund LO, Ward M; AddNeuroMed Consortium.
Plasma based markers of [11C] PiB-PET brain amyloid burden.
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Authors:
Kiddle SJ, Thambisetty M, Simmons A, Riddoch-Contreras J, Hye A, Westman E, Pike I, Ward M, Johnston C, Lupton MK, Lunnon K, Soininen H, Kloszewska I,Tsolaki M, Vellas B, Mecocci P, Lovestone S, Newhouse S, Dobson R; Alzheimers Disease Neuroimaging Initiative
Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's disease.
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Authors:
Güntert A, Campbell J, Saleem M, O'Brien DP, Thompson AJ, Byers HL, Ward MA, Lovestone S.
Glycosylation of Human Plasma Clusterin Yields a Novel Candidate Biomarker of Alzheimer's Disease.
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Authors:
Liang HC, Russell C, Mitra V, Chung R, Hye A, Bazenet C, Lovestone S, Pike I, Ward M.
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease.
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Authors:
Thambisetty M1, Simmons A, Velayudhan L, Hye A, Campbell J, Zhang Y, Wahlund LO, Westman E, Kinsey A, Güntert A, Proitsi P, Powell J, Causevic M, Killick R, Lunnon K, Lynham S, Broadstock M, Choudhry F, Howlett DR, Williams RJ, Sharp SI, Mitchelmore C, Tunnard C, Leung R, Foy C, O'Brien D, Breen G, Furney SJ, Ward M, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Hodges A, Murphy DG, Parkins S, Richardson JC, Resnick SM, Ferrucci L, Wong DF,Zhou Y, Muehlboeck S, Evans A, Francis PT, Spenger C, Lovestone S.
Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates.
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Authors:
Dalrymple A, Wild EJ, Joubert R, Sathasivam K, Björkqvist M, Petersén A, Jackson GS, Isaacs JD, Kristiansen M, Bates GP, Leavitt BR, Keir G, Ward M, Tabrizi SJ.
Evaluation of absolute peptide quantitation strategies using selected reaction monitoring.
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Authors:
Campbell J, Rezai T, Prakash A, Krastins B, Dayon L, Ward M, Robinson S, Lopez M.
Elevated levels of soluble total and hyperphosphorylated tau result in early behavioral deficits and distinct changes in brain pathology in a new tau transgenic mouse model.
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Authors:
Flunkert S, Hierzer M, Löffler T, Rabl R, Neddens J, Duller S, Schofield EL, Ward MA, Posch M, Jungwirth H, Windisch M, Hutter-Paier B
Stable mutated tau441 transfected SH-SY5Y cells as screening tool for Alzheimer's disease drug candidates.
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Authors:
Löffler T, Flunkert S, Taub N, Schofield EL, Ward MA, Windisch M, Hutter-Paier B.
Increased platelet expression of glycoprotein IIIa following aspirin treatment in aspirin-resistant but not aspirin-sensitive subjects.
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Authors:
Floyd CN, Goodman T, Becker S, Chen N, Mustafa A, Schofield E, Campbell J, Ward M, Sharma P, Ferro A.
Candidate verification of iron-regulated Neisseria meningitidis proteins using isotopic versions of tandem mass tags (TMT) and single reaction monitoring.
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Authors:
Byers HL, Campbell J, van Ulsen P, Tommassen J, Ward MA, Schulz-Knappe P, Prinz T, Kuhn K.
